DNA topoisomerase

DNA topoisomerase 基本解释

网络  拓朴异构酶; dna拓扑异构酶; 拓扑异构酶; 拓扑异构酶Ⅱ

化学

重点词汇

• DNA脱氧核糖核酸 [计] 无效数据, 数字网络体系结构, 分布式网络体系结构

DNA topoisomerase 双语例句

1. 1、 Screening of inhibitors of recombinant human DNA topoisomerase ⅰ from mangrove endophytic fungi
   从红树林内生真菌筛选重组人DNA拓扑异构酶Ⅰ抑制剂的研究
2. 2、 Development of DNA topoisomerase ⅱ inhibitors
   DNA拓扑异构酶Ⅱ抑制剂研究进展
3. 3、 Objective To study the effects of some biochemical factors on apoptosis in nasopharyngeal carcinoma cells ( CEN-2Z) induced by DNA topoisomerase I inhibitor camptothecin ( CPT).
   目的研究有关生化因素对喜树碱（CPT）诱导人鼻咽癌细胞凋亡的影响。
4. 4、 The alteration of content or activation of DNA topoisomerase;
   DNA拓扑异构酶含量及活性改变等。
5. 5、 Expression and clinical significance of DNA topoisomerase and glutathione S-transferases in acute leukemia
   DNA拓扑异构酶和谷胱甘肽S转移酶介导的机制在急性白血病临床耐药中作用的探讨
6. 6、 In addition, the paper reviewed screening methods for differentiation inducers, DNA topoisomerase inhibitors, antimicrotubule drugs and biological response modifiers.
   还对分化诱导剂、拓扑异构酶抑制剂、抗微管药和生物反应调节剂的筛选方法进行了评述。
7. 7、 Purification of DNA topoisomerase I from Rat Liver and Its Identification from B_2 Protein
   大鼠肝DNA拓扑异构酶Ⅰ的提纯及其与B2蛋白的鉴别
8. 8、 New research approaches in DNA topoisomerase ⅱ targets and antitumor drug
   DNA拓扑异构酶Ⅱ与抗肿瘤药物靶点的研究进展
9. 9、 Expression and Significance of DNA topoisomerase ⅱ in Esophageal Carcinoma
   DNA拓扑异构酶Ⅱ在食管癌的表达及意义
10. 10、 DNA topoisomerase type ⅱ and cell proliferation
    DNA拓扑异构酶Ⅱ与细胞增殖
11. 11、 The expression of glutathione-S-transferases-π and DNA topoisomerase in human osteosarcoma and their relationship to prognosis
    胎盘型谷胱甘肽-S-转移酶和DNA拓朴酶在人骨肉瘤中的表达及其与预后的关系
12. 12、 Background and purpose: Irinotecan ( CPT-11) is a derivative of camptothecin, an inhibitor of DNA topoisomerase I.
    背景与目的：伊立替康（CPT-11）是喜树碱类抗癌药物，为DNA拓扑异构酶Ⅰ抑制剂。
13. 13、 Purification and Characterization of DNA topoisomerase ⅰ From Human Spleen
    人脾DNA拓扑异构酶Ⅰ的提纯及其性质的研究
14. 14、 The resistance to a typical DNA topoisomerase II inhibitor VP16 ( Etoposide) was increased 9 times.
    对典型的DNA拓扑异构酶Ⅱ抑制刻VP16（Etoposide）抗药性增加9倍。
15. 15、 Expression of DNA topoisomerase ⅱ in proliferative cells
    DNA拓扑异构酶Ⅱ在增殖细胞中的表达及其意义
16. 16、 Optimization of the Expression of Human DNA topoisomerase ⅰ in Pichia pastoris
    人DNA拓扑异构酶Ⅰ在毕赤酵母中的表达及发酵条件优化
17. 17、 Glutathione S-transferase π, DNA topoisomerase ⅱ, and P-glycoprotein expression in brain of patients with refractory epilepsy
    谷胱甘肽S-转移酶π、DNA拓扑异构酶Ⅱ及P-糖蛋白在难治性癫癎患者脑内的表达
18. 18、 A comparative study of the biological activity of DNA topoisomerase I
    DNA拓扑异构酶Ⅰ生物学活性的比较研究
19. 19、 Anti-DNA topoisomerase ⅱ α autoantibodies in Japanese patients with systemic sclerosis
    日本系统性硬化症患者中的抗DNA拓扑异构酶Ⅱα自身抗体
20. 20、 The core event of cell proliferation is DNA replication and cell division. DNA topoisomerase type ⅱ plays an important role in this process.
    细胞增殖的核心事件是DNA复制与细胞分裂，DNA拓扑异构酶Ⅱ在该过程中起重要作用。
21. 21、 Experiments showed that the drugs which are able to intercalate into the supercoiled pBR322 DNA and induce DNA chain cleavage or inhibit the activity of DNA topoisomerase ⅱ would have antitumor effect.
    实验表明，对pBR322DNA能起嵌入和断裂作用或对DNA拓扑异构酶Ⅱ有抑制作用的化合物可能具有抗癌作用。
22. 22、 DNA topoisomerase and antitumor
    DNA拓扑异构酶与抗肿瘤
23. 23、 TPT is DNA topoisomerase I inhibitor.
    TPT是DNA拓扑异构酶Ⅰ抑制剂。
24. 24、 Screening of Antitumor Compounds from Natural Compounds or Its Derivatives by Using the Recombinant Human DNA topoisomerase ⅰ as Target
    以重组人DNA拓扑异构酶Ⅰ为靶位从天然产物及其衍生物中筛选抗肿瘤化合物
25. 25、 Expression of bcl 2 gene and DNA topoisomerase II activity were examined with Northern blot analysis and plasmid DNA breakage analysis, respectively.
    Northern杂交分析和质粒DNA断裂分析检测bcl2基因表达和DNA拓扑异构酶II活性。
26. 26、 AIM: To find natural DNA topoisomerase I inhibitors from Camptotheca acuminata Decne.
    目的以生物活性为向导在喜树中寻找天然的DNA拓扑异构酶I抑制剂。
27. 27、 Purpose To investigate the relationship between DNA topoisomerase and cell proliferation, apoptosis in ovarian carcinomas.
    目的：探讨DNA拓扑异构酶在卵巢浆液性、黏液性囊腺癌中的表达及与细胞增殖、凋亡的关系。
28. 28、 The activity of DNA topoisomerase was reduced.
    细胞内药物作用靶减少，拓扑异构酶活性降低；
29. 29、 The alteration of DNA gyrase and DNA topoisomerase IV is the main mechanism of resistance to fluoroquinolones in E. coli.
    DNA促旋酶和拓扑异构酶Ⅳ的改变是大肠埃希菌对氟喹诺酮类耐药的主要机制。